I think I don't have enough experience with them to say much, I bought a chemical fertilizer last growing season, but I didn't use much afraid of burning the plants since It's NOT encapsulated for slow releasing (Osmocote), so I rather preffer to use Castor Cake, which is easily available where I live, it's cheap (or free, if you willing to harvest/dry/mash them), and the results for me are really visible.
It would be interesting a side to side test, with plants at same stage, same conditions, and same genetics.
However, I don't think the difference would be big enough to be so relevant.
In the end, we should use what fits in our pockets, or for begginers like me, fool proof fertilizers. =]